Does CBD Help Migraines? A Comprehensive Analysis of Relief

Does CBD Help Migraines? A Comprehensive Analysis of Relief

The migraine sufferer’s search for relief leads down many paths. One path gaining attention is the use of Cannabidiol (CBD), a compound derived from the cannabis plant.

But, does CBD help migraines? And how does it compare to its more infamous cousin, THC?

Let’s delve into the science, research, benefits and potential risks associated with using CBD for migraines.

Key Takeaways

  • CBD’s interaction with the body’s endocannabinoid system (ECS) and its anti-inflammatory properties may offer potential relief from migraines by reducing pain perception and inflammation.
  • Existing research suggests that CBD could reduce the frequency and severity of migraines; however, evidence is not yet conclusive and more extensive clinical trials are needed to establish effectiveness and long-term impacts.
  • While CBD might provide migraine relief without psychoactive effects, THC also has potential benefits but with risks like worsened symptoms with excessive use; proper dosing and consultation with healthcare providers are critical before starting treatment.

    The Science Behind CBD and Migraines

    CBD oil and cannabis plant

    Our understanding of migraines has evolved significantly over the years. Recent research has shown the significant influence of our body’s endocannabinoid system in regulating migraines. This system is responsible for balancing various functions in the body, including pain perception. The introduction of cannabinoids, such as CBD, into this system could potentially offer relief from migraine symptoms.

    CBD, holding anti-inflammatory properties, can also be beneficial in treating migraines. As inflammation is often linked with migraines, CBD’s potential to curb it could potentially lessen migraine pain and other related symptoms.

    Endocannabinoid System

    The endocannabinoid system (ECS) is a complex network of receptors that interact with cannabinoids produced naturally by the body. These cannabinoids are quite similar to those found in the cannabis plant, such as CBD. The ECS plays a significant role in regulating various bodily functions, including:

    • Pain perception
    • Mood regulation
    • Sleep
    • Appetite
    • Immune function

      Upon entering the body, CBD interacts with ECS receptors, which could potentially offer a reprieve from migraine symptoms. The interaction between CBD and the ECS is believed to reduce migraine headache frequency and alleviate the severity of headache pain.

      Anti-Inflammatory Properties

      Numerous studies have acknowledged CBD’s anti-inflammatory properties, pointing to its potential to mitigate inflammation in conditions such as arthritis. But how does this relate to migraines? Well, inflammation is thought to play a role in contributing to migraine pain, and the ability of CBD to reduce this inflammation could potentially provide relief from pain and other related symptoms.

      Inflammation is often linked to the dilation of blood vessels, a condition also associated with migraines. Utilizing CBD’s anti-inflammatory properties could potentially reduce this inflammation, thereby lessening the severity of migraines.

      Research on CBD and Migraine Relief

      Research on CBD for migraines

      Despite the still developing scientific understanding of CBD’s role in alleviating migraines, initial research paints a promising picture. Studies have suggested that CBD could potentially reduce the frequency and severity of migraines. Additionally, patients have reported a decrease in headache and migraine severity after using cannabis.

      According to a study called Medical Cannabis, Headaches, and Migraines: A Review of the Current Literature, "The effect of medicinal cannabis on headaches and other conditions had a mean score of 3.6/5, which meant an 86% efficacy in pain relief."

      Nevertheless, these promising outcomes should be approached with caution. The research on CBD for migraines is still in its nascent stage, and while several studies show encouraging outcomes, the benefits and effectiveness of CBD for migraines are not yet supported by extensive clinical trials.

      Promising Results

      A number of studies have indicated positive results in relation to the usage of CBD for migraines. Patients have noticed substantial reductions in both the frequency and intensity of their migraines post CBD usage.

      One study called the Efficacy and Safety of Medical Marijuana in Migraine Headache: A Systematic Review reported that migraine sufferers who responded to cannabis treatment experienced a 50 percent reduction in their mean monthly migraine days.

      The study stated that "Patients were considered responders in the trial if their mean monthly migraine days decreased by at least 50%. In comparison to non-responders, respondents (n = 89, 61%) reported less current migraine disability and negative impact.."

      In addition to reducing migraine frequency, CBD may also help alleviate symptoms associated with migraines.

      Medical cannabis users have reported improved sleep quality, reduced nausea and vomiting, and even a decrease in the occurrence of acute migraine attacks, all of which can be attributed to medical cannabis use.

      Despite the uplifting results, it’s worth mentioning that CBD’s effects on migraines appear to decrease over time. This suggests a potential decline in efficacy with frequent usage, emphasizing the need for further research to fully understand the long-term impacts of CBD on migraines.

      The Need for Further Studies

      Although the initial findings seem promising, a broader research scope is needed to fully comprehend CBD’s potential in treating migraines. The current body of research lacks extensive studies on the endocannabinoid system’s involvement in migraines and the efficacy of medical cannabis.

      Moreover, there is a paucity of preclinical studies focusing specifically on the effectiveness of CBD for migraines. As a result, the optimal dosage, delivery methods, and long-term effects of CBD for migraines remain largely unknown.

      Future research could address these gaps by:

      • Conducting long-term clinical studies within a medicinal cannabis cohort, focusing on prolonged medical cannabis treatment
      • Analyzing potential differences in treatment outcomes across genders
      • Comparing CBD-exclusive therapy with cannabis containing THC
      • Comparing how the different isolated cannabinoids affect migraine treatment
      • Comparing how Full Spectrum vs Broad Spectrum vs Isolate CBD oil in treating migraine attacks
      • Comparing different marijuana strains, Indica vs Sativa in the medical treatment of headache symptoms

        CBD vs. THC: Which Is Better for Migraines?

        In the context of employing cannabis for migraines, a central debate often centers on the choice between CBD and THC. Both are compounds found in the cannabis plant, but they have different effects on the brain and body.

        While THC exerts psychoactive effects by interacting with the cannabinoid 1 (CB1) receptors, CBD regulates brain activity without inducing these effects, which may make it more suitable for migraine treatment.

        However, it’s noteworthy that both CBD and THC come with their own set of potential pros and cons in relation to migraine relief. The ideal choice depends on various factors, including the individual’s symptoms, tolerance, and personal preferences.

        Benefits of CBD

        CBD provides multiple advantages for those grappling with migraines. Its interaction with the endocannabinoid system can potentially provide relief from migraine symptoms such as severe headache pain, nausea, and swelling.

        More importantly, CBD does not induce the psychoactive effects associated with THC. This means that users can reap the potential benefits of CBD for migraines without experiencing a “high”.

        Moreover, CBD has the potential to reduce migraine frequency. By managing stress levels in the ECS, CBD can potentially reduce the likelihood of migraine onset and could be a promising addition to the migraine management toolkit.

        Drawbacks of THC

        Despite its possible upsides, THC carries its own challenges when utilized for migraine relief. The psychoactive effects of THC can result in:

        • Euphoria
        • Sedation
        • Elevated heart rate
        • Dry mouth
        • Reddening of the eyes
        • Heightened appetite
        • Paranoia

          Such side effects may not be conducive for individuals dealing with migraine headaches or medication overuse headache.

          Moreover, prolonged or excessive use of THC can lead to a worsening of migraine symptoms or an overall increase in discomfort. This is due to THC’s potential to affect the area of the brain associated with migraines.

          While THC can reduce the length and frequency of migraines, there are risks involved, especially with excessive use. These include the potential for negative side effects and the worsening of symptoms.

          How to Use CBD for Migraines

          CBD dosage considerations for migraines

          The use of CBD for migraines calls for multiple considerations. From choosing the right dosage to selecting the appropriate consumption method, there are various factors to keep in mind to ensure the effectiveness and safety of CBD for migraines.

          While the optimal dosage and consumption method can vary among individuals, starting with a low dose of 5-10mg and gradually increasing as needed is generally recommended. It’s also crucial to be aware of potential side effects and risks associated with using CBD for migraines.

          Dosage Considerations

          Establishing the fitting dosage of CBD for migraines is a vital aspect of its effective application. Starting with a low dose is advisable, and adjustments can be made based on the individual’s response to the treatment.

          The recommended initial dosage for CBD for migraines, is typically between 5 mg to 10 mg. This dosage can be adjusted based on individual factors such as:

          • The severity and frequency of migraines
          • Body weight
          • Metabolism
          • Tolerance
          • Body chemistry
          • Prior experience with CBD.
          • Use of other prescription medication
          • Use of other headache treatment supplements or over-the-counter medicine

            Gradually elevating the dosage until the desired relief is achieved is essential. It’s also crucial to keep in mind that everyone’s response to CBD can vary, so what works for one person may not work for another.

            Consumption Methods

            The mode of intake for CBD in the context of migraines can also impact its effectiveness. CBD can be consumed in various ways, including inhalation, ingestion, and topical application. Each method comes with its own set of advantages and disadvantages.

            • Smoking cannabis to inhale CBD

              • Advantage: Very short onset
              • Disadvantage: Dry mouth can lead to dehydration and lead to headache exacerbation
            • CBD gummies

              • Advantage: Tasty and easy to consume in public
              • Disadvantage: Longer onset time due to the absorption rate
            • CBD oils

              • Advantage: Easy and customizable dosing
              • Disadvantage: May look "druggy" or "taboo"

            Potential Side Effects and Risks

              Despite the potential upsides CBD may offer for migraines, it’s crucial to stay mindful of possible side effects and risks.

              For instance, while CBD cannot cause a lethal overdose, higher doses of CBD raise concerns about potential liver damage, which could be particularly relevant for individuals treating migraines.

              CBD may also interact with certain medications, including antiepileptic drugs like valproate and anti-migraine medications known as gepants.

              Therefore, it’s crucial to consult with a healthcare provider before starting CBD, especially if you’re taking other prescription medications.

              Additionally, frequent usage of CBD for migraines can potentially lead to the development of tolerance, impacting its long-term efficacy for certain individuals. This underscores the importance of starting with a low dose and gradually increasing as needed.

              Consult Your Healthcare Provider

              Considering the potential risks and side effects, it’s vital to consult a healthcare provider before initiating CBD usage for migraines. A healthcare provider can provide personalized guidance based on your specific symptoms, medical history, and other factors.

              Due to the complex nature of migraines and the lack of comprehensive research on CBD, if your pain intensity is severe or if you have debilitating headaches it is recommended to work with a healthcare provider who has firsthand experience in prescribing medical marijuana for migraine treatment, taking into account state medical marijuana laws. This might be better alternative therapy than purchasing hemp-derived products online.

              Ultimately, chronic migraine is a complex medical condition that requires a tailored treatment plan. Collaborating with a healthcare provider can ensure that all potential treatment options, including CBD, are considered and appropriately used.


              In conclusion, CBD holds potential as a remedy for migraines, thanks to its interaction with the endocannabinoid system and potential anti-inflammatory properties.

              Research indicates that CBD may help reduce the frequency and severity of migraines, although further studies are needed to fully understand its long-term effects and optimal dosage.

              While CBD may be a promising alternative to traditional migraine medications, it’s important to consult with a healthcare provider before starting treatment. This is especially true with medicinal cannabis use or those suffering from chronic pain or headache disorders.

              As with any treatment, a personalized approach that takes into account the individual’s symptoms, medical history, and other factors is crucial.

              Ready to fight the Sunday Scaries? Shop our CBD Gummies for FocusCBD CandyCBD Treats for DogsCBD GummiesCBD Oil TincturesCBD Sleep OilExtra Strength CBD Gummies, Delta-9 THC Gummies, CBD Edibles, and Vegan CBD Gummies online today!

              • Best Seller
                Stress Relief
                A 20-count bottle of Sunday Scaries CBD Gummies with tropical flavors and 10mg CBD per gummy

                CBD Gummies

                Rated 4.8 out of 5 stars
                1,040 Reviews

                CBD Gummies

              • Decompress
                Sunday Scaries - CBD Oil Tinctures for Stress Relief

                CBD Oil Tinctures

                Rated 4.8 out of 5 stars
                366 Reviews

                CBD Oil Tinctures

              • Best Seller
                Medium Dose
                A bottle of delta-9 THC gummies called Couch Potatoes with 5mg Delta 9 per gummy

                Delta-9 Gummies

                Rated 4.7 out of 5 stars
                132 Reviews

                Delta-9 Gummies